4-Ethynyl-N-ethyl-1,8-naphthalimide
Chemical Name: 2-Ethyl-6-ethynyl-1H-benz[de]isoquinoline
Purity: ≥98%
Biological Activity
Key information: 4-Ethynyl-N-ethyl-1,8-naphthalimide is a click-activated fluorescent probe, for cell surface imaging.Used for: imaging of cell surface and intracellular fucosylated glycoproteins and glycolipids.
Application: suitable for flow cytometry and fluorescence microscopy.
Properties and Photophysical Data: 4-Ethynyl-N-ethyl-1,8-naphthalimide is supplied with an azide reactive handle for copper-free click chemistry reactions.
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Chemical labeling of 5-iodo-2'-deoxyuridine with 4-ethynyl-N-ethyl-1,8-naphthalimide using copper-free Sonogashira cross-coupling in aqueous medium.
Yuan et al.
Synth.Commun., 2014;44:1007 -
Glycoproteomic probes for fluorescent imaging of fucosylated glycans in vivo.
Sawa et al.
Proc.Natl.Acad.Sci.U.S.A., 2006;103:12371
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