7-Nitroindazole

Biological Activity

Monosodium Salt also available.

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Background References

1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
   Fox JT, Sakamuru S, Huang R
   Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
2. Inhibition of rat cerebellar nitric oxide synthase by 7-nitroindazole and related substituted indazoles.
   Babbedge et al.
   Br.J.Pharmacol., 1993;110:225
3. 7-nitroindazole, an inhibitor of nitric oxide synthase, exhibits antinociceptive activity in the mouse without increasing blood pressure.
   Moore et al.
   Br.J.Pharmacol., 1993;108:296
4. Characterisation of the novel nitric oxide synthase inhibitor 7-nitroindazole and related indazoles: antinociceptive and cardiovascular effects.
   Moore et al.
   Br.J.Pharmacol., 1993;110:219
5. Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system?
   Moore and Handy
   TiPS, 1997;18:204

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