8-Hydroxy-PIPAT oxalate
Chemical Name: (RS)-trans-8-Hydroxy-2-[N-n-propyl-N-(3'-iodo-2'-propenyl)amino]tetralin oxalate
Purity: ≥98%
Biological Activity
8-Hydroxy-PIPAT oxalate is a high affinity 5-HT1A receptor agonist (Kd = 0.38 nM).7-Hydroxy Isomer also available.
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Fox JT, Sakamuru S, Huang R
Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. -
Synthesis of (R,S)-trans-8-Hydroxy-2-[N-n-propyl-N-(3'-iodo-2'-propenyl)amino]tetralin (trans-8-OH-PIPAT): a new 5-HT1A receptor ligand.
Zhuang et al.
J.Med.Chem., 1993;36:3161
Product Datasheets
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