A 205804

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. Host ICAMs play a role in cell invasion by Mycobacterium tuberculosis and Plasmodium falciparum.
   Bhalla, Kuhulika, Chugh, Monika, Mehrotra, Sonali, Rathore, Sumit, Tousif, Sultan, Prakash Dwivedi, Ved, Prakash, Prem, Kumar Samuchiwal, Sachin, Kumar, Sushil, Kumar Singh, Dhiraj, Ghanwat, Swapnil, Kumar, Dhiraj, Das, Gobardha, Mohmmed, Asif, Malhotra, Pawan, Ranganathan, Anand
   Nat Commun, 2015;6(0):6049.
2. Discovery of inhibitors of cell adhesion molecule expression in human endothelial cells. 1. Selective inhibition of ICAM-1 and E-selectin expression.
   Stewart et al.
   J.Med.Chem., 2001;44:988
3. Selective inhibition of ICAM-1 and E-selectin expression in human endothelial cells. 2. Aryl modifications of 4-(aryloxy)thieno[2,3-c]pyridines with fine-tuning at C-2 carbamides.
   Zhu et al.
   J.Med.Chem., 2001;44:3469
4. Synthesis and mode of action of ¹²⁵I- and ³H-labeled thieno[2,3-c]pyridine antagonists of cell adhesion molecule expression.
   Zhu et al.
   J.Org.Chem., 2002;67:943

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