Alprenolol hydrochloride
Chemical Name: 1-[(1-Methylethyl)amino]-3-[2-(2-propenyl)phenoxy]-2-propanol hydrochloride
Purity: ≥99%
Biological Activity
Alprenolol hydrochloride is a β-adrenoceptor (β2 > β1 > β3) and 5-HT1A receptor antagonist.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Antagonist characterization of atypical beta adrenoceptors in guinea pig ileum: blockade by alprenolol and dihydroalprenolol.
Blue et al.
J.Pharmacol.Exp.Ther., 1990;252:1034 -
The 5-HT1A antagonist (-)-alprenolol fails to modify sleep or zimeldine-induced sleep-waking effects in rats.
Bjorvatin et al.
Pharmacol.Biochem.Behav., 1992;42:49 -
The selectivity of β-adrenoceptor antagonists at the human β1, β2 and β3 adrenoceptors.
Baker
Br.J.Pharmacol., 2005;144:317
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