Amiloride hydrochloride

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. Diuretic sensitive electroneutral Na(+) movement and temperature effects on central axons
   M Kanagaratn, C Pendleton, DA Souza, J Pettit, J Howells, MD Baker
   J. Physiol. (Lond.), 2017;0(0):.
2. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
   Fox JT, Sakamuru S, Huang R
   Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
3. Evaluation of the role of nitric oxide in acid sensing ion channel mediated cell death.
   Jetti et al.
   Nitric Oxide, 2010;22:213
4. The pharmacology of mechanogated membrane ion channels.
   Hamill and McBride
   Pharmacol.Rev., 1996;48:231
5. Amiloride and its analogues as tools in the study of ion transport.
   Kleyman et al.
   J.Membr.Biol., 1988;105:1
6. A second generation of centrally acting antihypertensive agents act on putative I₁-imidazoline receptors.
   Ernsberger et al.
   J.Cardiovasc.Pharmacol., 1992;20:S1
7. Inhibition of TRPP₃ channel by amil. and analogs.
   Dai et al.
   Mol.Pharmacol., 2007;72:1576

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