Amperozide hydrochloride

Name: Amperozide hydrochloride
Brand: Tocris Bioscience
SKU: 2746

Catalog #: 2746 Datasheet / COA / SDS

Discontinued Product

2746 has been discontinued.

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Amperozide hydrochloride | CAS No. 86725-37-3 | Additional Non-selective 5-HT2 Receptor Products

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Description: Atypical antipsychotic; high affinity 5-HT2 ligand

Alternative Names: FG 5606

Chemical Name: 4-[4,4-bis(4-Fluorophenyl)butyl]-N-ethyl-1-piperazinecarboxamide hydrochloride

Purity: ≥99%

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Product Details

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Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Atypical antipsychotic that displays high affinity for 5-HT₂ receptors (K_i = 26 nM) and low affinity for D₂ receptors. Supresses ethanol drinking in genetically ethanol-preferring rats.

Technical Data

M.Wt:

437.95

Formula:

C₂₃H₂₉F₂N₃O.HCl

Solubility:

Soluble to 50 mM in water

Purity:

≥99%

Storage:

Store at +4°C

CAS No:

86725-37-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

Effect of amperozide on rat cortical 5-HT₂ and striatal and limbic DA D₂ receptor occupancy: implications for antipsychotic action.
Meltzer et al.
Eur.J.Pharmacol., 1992;216:67

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