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Amylin (rat)

Catalog #: 6030 Datasheet / COA / SDS

Discontinued Product

6030 has been discontinued.
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Amylin (rat)
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Description: Potent endogenous peptide agonist for amylin, calcitonin, CGRP and adrenomedullin receptors
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Biological Activity

Amylin (rat) is a potent endogenous peptide agonist for amylin, calcitonin, CGRP and adrenomedullin receptors (pEC50 values are 7.06-9.50 at hCTa, 8.11 at rCTa, 7.73-10.1 at hAMY1a, 9.74 at rAMY1a, 7.92 at hAMY1b, 7.78-9.9 at hAMY2a, 7.94 at hAMY2b, 8.09-10.8 at hAMY3a, 9.97 at rAMY and 8.19 at hAMY3b) receptors. Suppresses insulin-stimulated glucose uptake. Delays gastric emptying and promotes satiety. Active in vivo.

Technical Data

M.Wt:
3920.43
Formula:
C167H272N52O53S2
Sequence:
KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY

(Modifications: Tyr-37 = C-terminal amide, Disulfide bridge between 2 - 7)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Store at -20°C
CAS No:
124447-81-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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