Apelin-17 (human, bovine)
Purity: ≥95%
Biological Activity
Apelin-17 (human, bovine) is an endogenous apelin receptor agonist. Potently inhibits forskolin-stimulated cAMP accumulation (pIC50 = 9.94).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Pharmacological and immunohistochemical characterization of the APJ receptor and its endogenous ligand apelin.
Medhurst et al.
J.Neurochem., 2003;84:1162 -
Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor.
Tatemoto et al.
Biochem.Biophys.Res.Comms., 1998;251:471 -
Apelin, a potent diuretic neuropeptide counteracting vasopressin actions through inhibition of vasopressin neuron activity and vasopressin release.
De Mota et al.
Proc.Natl.Acad.Sci. USA, 2004;101:10464
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Citation for Apelin-17 (human, bovine)
The citations listed below are publications that use Tocris products. Selected citations for Apelin-17 (human, bovine) include:
1 Citation: Showing 1 - 1
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A Differential Hypofunctionality of Gαi Proteins Occurs in Adolescent Idiopathic Scoliosis and Correlates with the Risk of Disease Progression.
Authors: Akoume Et al.
Sci Rep 2019;9:10074
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