Arecaidine propargyl ester tosylate
Chemical Name: N-Methyl-1,2,5,6-tetrahydropyridine-3-carboxylic acid propargyl ester tosylate
Biological Activity
Arecaidine propargyl ester tosylate is an a potent muscarinic receptor agonist. Shows some selectivity for cardiac versus ileal M2 receptors.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Fox JT, Sakamuru S, Huang R
Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. -
The relative potencies of some agonists at M2 muscarinic receptors in guinea pig ileum, atria and bronchi.
Barlow and Weston-Smith
Br.J.Pharmacol., 1985;85:437 -
Structure-activity relationships of new analogues of arecaidine propargyl ester at muscarinic M1 and M2 receptor subtypes.
Moser et al.
Br.J.Pharmacol., 1989;96:319
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