AZD 2066
Chemical Name: 4-[5-[(1R)-1-[5-(3-Chlorophenyl)-3-isoxazolyl]ethoxy]-4-methyl-4H-1,2,4-triazol-3-yl]pyridine
Purity: ≥98%
Biological Activity
AZD 2066 is an mGlu5 antagonist. Displays discriminative effects in rats. Orally bioavailable and brain penetrant.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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AZD9272 and AZD2066: selective and highly central nervous system penetrant mGluR5 antagonists characterized by their discriminative effects.
Swedberg et al.
J.Pharmacol.Exp.Ther., 2014;350:212
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