BAM (8-22)

Catalog # Availability Size / Price Qty
1763/1
BAM (8-22)
1 Image
Description: Potent MRGPRX1 agonist

Purity: ≥95%

Product Details
Citations (5)
Reviews

Biological Activity

BAM (8-22) is an endogenous peptide fragment that is a potent agonist for MRGPRX1 (EC50 values are 8 - 150 nM). It was first isolated from bovine adrenal medulla. Unlike BAM 22P (Cat. No. 1650), BAM (8-22) does not contain the met-enkephalin motif therefore displays no affinity for opioid receptors. BAM (8-22) augments scratching behavior in a cholestatic pruritus mice model. BAM (8-22) attenuates bone cancer pain in mice.

Technical Data

M.Wt:
1971.22
Formula:
C91H127N25O23S
Sequence:
VGRPEWWMDYQKRYG
Solubility:
Soluble to 1 mg/ml in water
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
412961-36-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for BAM (8-22)

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