BAPTA
Chemical Name: 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid
Purity: ≥95%
Biological Activity
BAPTA is a selective calcium chelator.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Role of focal adhesion tyrosine kinases in GPVI-dependent platelet activation and reactive oxygen species formation.
Carrim N, Walsh T, Consonni A, Torti M, Berndt M, Metharom P
PLoS ONE, 2014;9(11):e113679. -
Inhibition of phospholipase C activity in Drosophila photoreceptors by 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid (BAPTA) and di-bromo BAPTA.
Hardie
Cell Calcium, 2005;38:547
Product Datasheets
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Citations for BAPTA
The citations listed below are publications that use Tocris products. Selected citations for BAPTA include:
17 Citations: Showing 1 - 10
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A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells.
Authors: Chefetz Et al.
Cell Rep 2019;26:3061
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Input-Timing-Dependent Plasticity in the Hippocampal CA2 Region and Its Potential Role in Social Memory.
Authors: Leroy Et al.
Neuron 2017;95:1089
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Calcium-regulatory proteins as modulators of chemotherapy in human neuroblastoma.
Authors: Florea Et al.
Oncotarget 2017;8:22876
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mGluR long-term depression regulates GluA2 association with COPII vesicles and exit from the endoplasmic reticulum.
Authors: Pick Et al.
EMBO J 2017;36:232
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Presynaptic Spike Timing-Dependent Long-Term Depression in the Mouse Hippocampus.
Authors: Andrade-Talavera Et al.
Cereb Cortex 2016;26:3637
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Calcium flux-independent NMDA receptor activity is required for Aβ oligomer-induced synaptic loss.
Authors: Birnbaum Et al.
PLoS One 2015;6:e1791
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Sex Differences in Molecular Signaling at Inhibitory Synapses in the Hippocampus.
Authors: Tabatadze Et al.
J Neurosci 2015;35:11252
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NPY signaling inhibits extended amygdala CRF neurons to suppress binge alcohol drinking.
Authors: Pleil Et al.
Nat Neurosci 2015;18:545
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A critical role for the transient receptor potential channel type 6 in human platelet activation.
Authors: Vemana Et al.
Cell Commun Signal 2015;10:e0125764
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Purines released from astrocytes inhibit excitatory synaptic transmission in the ventral horn of the spinal cord.
Authors: Carlsen and Perrier
Front Neural Circuits 2014;8:60
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Distinct molecular components for thalamic- and cortical-dependent plasticity in the lateral amygdala.
Authors: Mirante Et al.
Cell Death Dis 2014;7:62
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DArgic modulation of GABAergic transmission in the entorhinal cortex: concerted roles of α1 adrenoreceptors, inward rectifier K+, and T-type Ca2+ channels.
Authors: Cilz Et al.
Cereb Cortex 2014;24:3195
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Synaptic NMDA receptor-dependent Ca2+ entry drives membrane potential and Ca2+ oscillations in spinal ventral horn neurons.
Authors: Alpert and Alford
PLoS One 2013;8:e63154
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Synaptotagmin-12 phosphorylation by cAMP-dependent protein kinase is essential for hippocampal mossy fiber LTP.
Authors: Kaeser-Woo Et al.
J Neurosci 2013;33:9769
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Astrocytes mediate in vivo cholinergic-induced synaptic plasticity.
Authors: Navarrete Et al.
PLoS Biol 2012;10:e1001259
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Oncogenic BRAF induces melanoma cell invasion by downregulating the cGMP-specific phosphodiesterase PDE5A.
Authors: Arozarena Et al.
Cancer Cell 2011;19:45
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Phorbol 12-myristate 13-acetate potentiation of N-MthD.-aspartate-induced currents in primary cultured cerebellar granule cells is mediated by protein kinase C alpha.
Authors: Reneau Et al.
J Pharmacol Exp Ther 2009;330:641
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