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Benazepril hydrochloride

Catalog #: 2578
3 Citations Datasheet / COA / SDS

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2578 has been discontinued.
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Benazepril hydrochloride | CAS No. 86541-74-4 | ACE Inhibitors
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Description: Angiotensin-converting enzyme (ACE) inhibitor
Alternative Names: CGS 14824A

Chemical Name: (3S)-3-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid hydrochloride

Purity: ≥99%

Product Details
Citations (3)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Benazepril hydrochloride is a non-peptide angiotensin-converting enzyme (ACE) inhibitor. Reduces blood pressure and myocardial hypertrophy in spontaneous hypertensive rats.

Technical Data

M.Wt:
460.96
Formula:
C24H28N2O5.HCl
Solubility:
Soluble to 50 mM in water and to 100 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at +4°C
CAS No:
86541-74-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Hemodynamic effects of benazepril, an angiotensin-converting enzyme inhibitor, as studied in conscious normotensive dogs.
    Ishibashi et al.
    Cardiovas.Drugs Ther., 1991;5:635
  2. Effect of benaz. hydrochloride on cardiac hypertrophy in spontaneous hypertensive rats.
    Takemori et al.
    Arzneim.-Forsch., 1991;41:612
  3. General pharmacology of the novel angiotensin converting enzyme inhibitor benaz. hydrochloride. Effects on cardiovascular, visceral and renal functions and on hemodynamics.
    Yamamoto et al.
    Arzneim.-Forsch., 1991;41:913

Product Datasheets

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Citations for Benazepril hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Benazepril hydrochloride include:

3 Citations: Showing 1 - 3

  1. Characterization of UDP-Activated Purinergic Receptor P2Y6 Involved in Japanese Flounder Paralichthys olivaceus Innate Immunity.
    Authors: Li Et al.
    Int J Mol Sci  2018;19
  2. Quantitative Analyses of Synergistic Responses between Cannabidiol and DNA-Damaging Agents on the Proliferation and Viability of Glioblastoma and Neural Progenitor Cells in Culture.
    Authors: Deng Et al.
    J Pharmacol Exp Ther  2017;360:215
  3. NTPDase1 activity attenuates microglial phagocytosis.
    Authors: Bulavina Et al.
    Purinergic Signal  2013;9:199

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