Bifemelane hydrochloride
Chemical Name: 4-(2-Benzylphenoxy)-N-methylbutylamine hydrochloride
Purity: ≥99%
Biological Activity
Bifemelane hydrochloride is an antidepressant MAO inhibitor. Reverses catalepsy induced by Tetrabenazine (Cat. No. 2175) in mice and increases locomotor activity in MPTP-treated marmosets.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Fox JT, Sakamuru S, Huang R
Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. -
4-(o-benzylphenoxy)-N-methylbutylamine (bifemelane) and other 4-(o-benzylphenoxy)-N-methylalkylamines as new inhibitors of type A and B monoamine oxidase.
Naoi et al.
J.Neurochem., 1988;50:243 -
Effects of bifemelane on parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the common marmoset.
Nomoto et al.
Neurosci.Lett., 1994;178:95 -
Pharmacological evaluation of 2-(4-methylaminobutoxy)diphenylmethane hydrochloride (MCl-2016), a new psychotropic drug with antidepressant activity.
Tobe et al.
Arzneimittelforschung, 1981;31:1278
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