BIM 23052

Name: BIM 23052
Brand: Tocris Bioscience
SKU: 2842

Catalog #: 2842 Datasheet / COA / SDS

Discontinued Product

2842 has been discontinued.

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Description: sst5 agonist

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Product Details

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Biological Activity

Somatostatin sst₅ receptor agonist (K_i values are 7.3, 13.5, 31.3 and 141 nM for sst₅, sst₂, sst₁ and sst₄ receptors respectively). Stimulates gastric emptying following i.c. administration.

Technical Data

M.Wt:

1122.3

Formula:

C₆₁H₇₅N₁₁O₁₀

Sequence:

FFFWKTFT

(Modifications: Phe-1 = D-Phe, Trp-4 = D-Trp, Thr-8 = C-terminal amide)

Solubility:

Soluble to 1 mg/ml in water

Storage:

Store at -20°C

CAS No:

133073-82-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

Subtype selectivity of peptide analogs for all five cloned human somatostatin receptors (hsstr 1-5).
Patel and Srikant
Endocrinology, 1994;135:2814
Intracisternal injection of somatostatin receptor 5-preferring agonists induces a vagal cholinergic stimulation of gastric emptying in rats.
Martinez et al.
J.Pharmacol.Exp.Ther., 2000;293:1099
Pharmacological characterisation of the goldfish somatostatin sst5 receptor.
Nunn et al.
Eur.J.Pharmacol., 2002;436:173

Product Datasheets

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

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