BIO-acetoxime

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. Frat2 mediates the oncogenic activation of Rac by MLL fusions.
   Walf-Vorderwulbecke V, de Boer J, Horton S, van Amerongen R, Proost N, Berns A, Williams O
   Blood, 2012;120(24):4819-28.
2. GSK-3-selective inhibitors derived from tyrian purple indirubins.
   Meijer et al.
   Chem.Biol., 2003;10:1255
3. Structural basis for the synthesis of indirubins as potent and selective inhibitors of glycogen synthase kinase-3 and cyclin-dependent kinases.
   Polychronopoulos et al.
   J.Med.Chem., 2004;47:935
4. Wnt signaling arrests T cell differentiation and generates CD8+ memory stem cells.
   Gattinoni et al.
   Nat.Med., 2009;15:808

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