BML 111
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Description: FPR2 (lipoxin A4 receptor) agonist
Chemical Name: (5S,6R)-Methyl 5,6,7-trihydroxyheptanoate
Biological Activity
BML 111 is a FPR2 (lipoxin A4 receptor) agonist. Suppresses tumor-related angiogenesis and reduces tumor growth in hepatoma H22 cell bearing mice. Also protects against hemorrhagic shock-induced acute lung injury in rats. Lipoxin A4 analog.Technical Data
M.Wt:
192.21
Formula:
C8H16O5
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Storage:
Store at -20°C
CAS No:
78606-80-1
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Lipoxin A4 and its analogue suppress the tumor growth of transplanted H22 in mice: the role of antiangiogenesis.
Chen et al.
Mol.Cancer.Ther., 2010;9:2164 -
BML-111, a lipoxin receptor agonist, protects haemorrhagic shock-induced acute lung injury in rats.
Gong et al.
Resuscitation., 2012;83:907
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