BMY 45778
Chemical Name: [3-(4,5-Diphenyl[2,4'-bioxazol]-5'-yl)phenoxy]acetic acid
Purity: ≥99%
Biological Activity
BMY 45778 is a non-prostanoid prostacyclin mimetic that acts as a partial agonist at IP1 prostacyclin receptors. Potently inhibits platelet aggregation in vitro (IC50 = 27-35 nM).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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Non-prostanoid prostacyclin mimetics as neuronal stimulants in the rat: comparison of vagus nerve and NANC innervation of the colon.
Rudd et al.
Br.J.Pharmacol., 2000;129:782 -
[3-[4-(4,5-Diphenyl-2-oxazolyl)-5-oxazolyl]phenoxy]acetic acid (BMY 45778) is a potent non-prostanoid prostacyclin partial agonist: effects on platelet aggregation, adenylyl cyclase, cAMP levels, protein kinase, and ilo. binding.
Seiler et al.
Prostaglandins, 1997;53:21
Product Datasheets
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