Boc-Leu-Arg-Arg-AMC (Boc-LRR-AMC)
Boc-Leu-Arg-Arg-AMC (Boc-LRR-AMC) Summary
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Product Datasheets
Citations for Boc-Leu-Arg-Arg-AMC (Boc-LRR-AMC)
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 8
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Activation mechanism and activity of globupain, a thermostable C11 protease from the Arctic Mid-Ocean Ridge hydrothermal system
Authors: V Røyseth, BM Hurysz, A Kaczorowsk, S Dorawa, AE Fedøy, H Arsin, M Serafim, O Werbowy, T Kaczorowsk, R Stokke, AJ O'Donoghue, IH Steen
bioRxiv : the preprint server for biology, 2023-04-04;0(0):. 2023-04-04
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Differential Effects of Nonsteroidal Anti-Inflammatory Drugs in an In Vitro Model of Human Leaky Gut
Authors: M d'Angelo, L Brandolini, M Catanesi, V Castelli, C Giorgio, M Alfonsetti, M Tomassetti, M Zippoli, E Benedetti, MC Cesta, S Colagioia, P Cocchiaro, A Cimini, M Allegretti
Cells, 2023-02-24;12(5):. 2023-02-24
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Piperlongumine overcomes imatinib resistance by inducing proteasome inhibition in chronic myelogenous leukemia cells
Authors: X Lan, M Hu, L Jiang, J Wang, Y Meng, X Chen, A Liu, W Ding, H Zhang, H Zhou, B Liu, G Peng, S Liao, X Chen, J Liu, X Shi
Journal of ethnopharmacology, 2022-10-08;301(0):115815. 2022-10-08
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Neurotoxicity of a pyrethroid pesticide deltamethrin is associated with the imbalance in proteolytic systems caused by mitophagy activation and proteasome inhibition
Authors: T Hirano, N Suzuki, Y Ikenaka, N Hoshi, Y Tabuchi
Toxicology and Applied Pharmacology, 2021-09-11;430(0):115723. 2021-09-11
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NSAIDs-dependent adaption of the mitochondria-proteasome system in immortalized human cardiomyocytes
Authors: L Brandolini, A Antonosant, C Giorgio, M Bagnasco, M d'Angelo, V Castelli, E Benedetti, A Cimini, M Allegretti
Sci Rep, 2020-10-27;10(1):18337. 2020-10-27
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A new gold(I) complex-Au(PPh3)PT is a deubiquitinase inhibitor and inhibits tumor growth
Authors: X Li, Q Huang, H Long, P Zhang, H Su, J Liu
EBioMedicine, 2018-12-05;0(0):. 2018-12-05
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Platinum pyrithione induces apoptosis in chronic myeloid leukemia cells resistant to imatinib via DUB inhibition-dependent caspase activation and Bcr-Abl downregulation
Authors: X Lan, C Zhao, X Chen, P Zhang, D Zang, J Wu, J Chen, H Long, L Yang, H Huang, X Wang, X Shi, J Liu
Cell Death Dis, 2017-07-06;8(7):e2913. 2017-07-06
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Curcumin Improves Palmitate-Induced Insulin Resistance in Human Umbilical Vein Endothelial Cells by Maintaining Proteostasis in Endoplasmic Reticulum
Authors: M Ye, H Qiu, Y Cao, M Zhang, Y Mi
Front. Pharmacol, 2017-03-21;8(0):148. 2017-03-21
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S-300 hydrolysis confirmation by LCMS-SRM
S-300: 1 uM
i20S: 15 nM
PA28a: 150 nM
Reaction: 37 °C for 5 h
1:S-300 Boc-LRR-AMC (351.20>301.30)
2:Free AMC (176.25>120.00)
3:S-300 Boc-LRR-COOH (272.70>222.15)
Ordinate: fluorescent count, Em 345/Ex 445
Em band path: 9 nm
Ex band path: 20 nm
Horizontal: time [sec]
Temp: 37 °C
S-300: 20 nM
Trypsin: 10 ng per assay (100 uL)
T1-T6: S-300/Trypsin (N=6)
Sub: S-300 and Tris buffer
Buffer: Tris buffer only
S-300 has very low level of intrinsic fluorescence but does not interfere the sample assay.
