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Bombinakinin M

Catalog #: 2371 Datasheet / COA / SDS

Discontinued Product

2371 has been discontinued.
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Bombinakinin M
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Description: Potent bradykinin agonist
Alternative Names: Maximakinin
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Biological Activity

Bombinakinin M is a potent bradykinin receptor agonist. Highly selective for mammalian arterial smooth muscle bradykinin receptors, displaying ~ 50-fold greater potency than bradykinin. Elicits dose-dependent contractile effects in smooth muscle of guinea pig ileum (EC50 = 4.0 nM).

Technical Data

M.Wt:
2179.55
Formula:
C100H159N31O24
Sequence:
DLPKINRKGPRPPGFSPFR
Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
509151-65-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. A novel bradykinin-related peptide from skin secretions of toad Bombina maxima and its precursor containing six identicals copies of the final product.
    Lai et al.
    Biochem.Biophys.Res.Comm., 2001;286:259
  2. The smooth muscle pharmacology of maximakinin, a receptor-selective, bradykinin-related nonadecapeptide from the venom of the Chinese toad, Bombina maxima.
    O'Rourke et al.
    Regul.Peptides, 2004;121:65
  3. Cloning of bradykinin precursor cDNAs from skin of Bombina maxima reveals novel bombinakinin M antagonists and a bradykinin potential peptide.
    Lee et al.
    Regul.Peptides, 2005;127:207

Product Datasheets

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