Home / Class I Histone Deacetylases Inhibitors / BRD 73954

BRD 73954

Catalog #: 6284 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6284/10
6284/50
BRD 73954 | CAS No. 1440209-96-0 | Class I Histone Deacetylases Inhibitors
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Description: Dual histone deacetylase (HDAC) 6/8 inhibitor

Chemical Name: N1-Hydroxy-N3-(2-phenylethyl)-1,3-benzenedicarboxamide

Purity: ≥98%

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Biological Activity

BRD 73954 is a dual histone deacetylase (HDAC) 6/8 inhibitor. IC50 values are 0.036 μM, 0.12 μM, 9 μM, >33 μM, for HDAC6, HDAC8, HDAC2 and HDAC4, respectively.

Technical Data

M.Wt:
284.31
Formula:
C16H16N2O3
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol with gentle warming
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
1440209-96-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Discovery of the first histone deacetylase 6/8 dual inhibitors.
    Olson et al.
    J.Med.Chem., 2013;56:4816

Product Datasheets

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