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BTD S-sulfenic acid probe

Catalog #: 8059 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
8059/10
BTD S-sulfenic acid probe | CAS No. 2095485-22-4 | General Laboratory Research Reagent
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Description: Chemoproteomic reagent for targeting S-sulfenic acids on SulfenQ platform, alkyne handle for click chemistry

Chemical Name: 1-(4-Pentyn-1-yl)-1H-2,1-benzothiazin-4(3H)-one 2,2-dioxide

Purity: ≥98%

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Biological Activity

BTD S-sulfenic acid probe is a nucleophilic fragment that can selectively modify sulfenic acid residues in proteins, and can be used as a tool to identify ligandable S-sulfenation sites. Covalently modifies oxidized cysteines on proteins. Quantitatively labels hyper-reactive sulfenic acids at low BTD concentrations, less reactive sites exhibit concentration-dependent increases in probe labeling. Incorporates an alkyne handle for click chemistry and chemoproteomic profiling.

Technical Data

M.Wt:
263.31
Formula:
C13H13NO3S
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
2095485-22-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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