BU 226 hydrochloride
Discontinued Product
Chemical Name: 2-(4,5-Dihydroimidazol-2-yl)isoquinoline hydrochloride
Biological Activity
BU 226 hydrochloride is a high affinity ligand for I2 imidazoline sites (Ki = 2.7 nM) with very high selectivity (> 2000-fold) over α2-adrenoceptors (Ki = 6700 nM).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Fox JT, Sakamuru S, Huang R
Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. -
Novel selective compounds for the investigation of imidazoline receptors.
Hudson et al.
Ann.N.Y.Acad.Sci., 1999;881:81 -
BU226: A selective ligand for rat brain imidazoline I2 sites.
Lione et al.
Soc.Neurosci.Abstr., 1997;23:695.28
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Citation for BU 226 hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for BU 226 hydrochloride include:
1 Citation: Showing 1 - 1
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Activation of the extraneuronal monoamine transporter (EMT) from rat expressed in 293 cells.
Authors: Gründemann Et al.
Br J Pharmacol 2002;137:910
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