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BU 239 hydrochloride

Catalog #: 0726 Datasheet / COA / SDS

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BU 239 hydrochloride | CAS No. 1217041-98-9 | Imidazoline 2 (I2) Receptor Ligands
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Description: Potent, highly selective I2 ligand

Chemical Name: 2-(4,5-Dihydroimidazol-2-yl)quinoxaline hydrochloride

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Biological Activity

BU 239 hydrochloride is a high affinity ligand for the imidazoline I2 binding site.

Technical Data

M.Wt:
234.69
Formula:
C11H10N4.HCl
Solubility:
Soluble to 50 mM in DMSO
Storage:
Desiccate at RT
CAS No:
1217041-98-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
    Fox JT, Sakamuru S, Huang R
    Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
  2. Affinity and selectivity of BU224 and BU239 for rabbit brain non-adrenoceptor idazoxan binding sites (I2 sites).
    Hudson et al.
    Br.J.Pharmacol., 1994;112:320P
  3. Affinity and selectivity of BU 224 and BU 239 for rat and guinea-pig brain I2 imidazoline sites.
    Lione et al.
    Br.J.Pharmacol., 1996;117:297P

Product Datasheets

Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
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