Buprenorphine hydrochloride
Discontinued Product
Chemical Name: [5α,7α(S)]-17-(Cyclopropylmethyl)-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-6,14-ethenomorphinan-7-methanol hydrochloride
Purity: ≥99%
Biological Activity
Buprenorphine hydrochloride is a ORL1 receptor agonist that also displays mixed antagonist/partial agonist activity at κ, δ and μ-opioid receptors.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Agonist effect of Bupren. in a nociceptin/OFQ receptor-triggered reporter gene assay.
Wnendt et al.
Mol.Pharmacol., 1999;56:334 -
Behavioral pharmacology of Bupren., with a focus on preclinical models of reward and addiction.
Tzschentke
Psychopharmacology, 2002;161:1
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Citation for Buprenorphine hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for Buprenorphine hydrochloride include:
1 Citation: Showing 1 - 1
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Cell-Autonomous Regulation of Dendritic Spine Density by PirB.
Authors: Vidal Et al.
Eneuro 2016;3
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