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Cannabigerol

Catalog #: 3021 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3021/10
Cannabigerol | CAS No. 25654-31-3 | Non-selective Cannabinoid Receptor Agonists
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Description: Cannabinoid receptor partial agonist

Chemical Name: 2-[(2E)-3,7-Dimethyl-2,6-octadienyl)-5-pentyl-1,3-benzenediol

Purity: ≥95%

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Biological Activity

Cannabigerol is a partial agonist of CB2 and CB1 receptors (Ki values are 337 and 440 nM respectively). Also exhibits α2-adrenoceptor agonist activity (EC50 = 0.2 nM in mouse brain membranes).

Technical Data

M.Wt:
316.48
Formula:
C21H32O2
Solubility:
Soluble to 100 mM in ethanol and to 100 mM in DMSO
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
25654-31-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Cannabigerol behaves as a partial agonist at both CB1 and CB2 receptors.
    Gauson et al.
    Symposium on the Cannabinoids, 2007;:206
  2. Evidence that the plant cannabinoid cannabigerol is a highly potent α2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist.
    Cascio et al.
    Br.J.Pharmacol., 2010;159:129
  3. The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin.
    Pertwee
    Br.J.Pharmacol., ;153:199

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