Cerulenin

Catalog #: 6702 Datasheet / COA / SDS

Discontinued Product

6702 has been discontinued.
View all Fatty Acid Synthase Inhibitors products.
Cerulenin | CAS No. 17397-89-6 | Fatty Acid Synthase Inhibitors
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Description: Irreversible fatty acid synthase inhibitor

Chemical Name: (2R,3S)-3-[(4E,7E)-1-Oxo-4,7-nonadien-1-yl]-2-oxiranecarboxamide

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Biological Activity

Cerulenin is an irreversible fatty acid synthase inhibitor. Blocks proliferation of KRAS-driven lung cancer cells. Promotes apoptosis and inhibits necroptosis in cancer cells. Also inhibits protein palmitoylation and insulin uptake in rat adipocytes in vitro. Antibiotic.

Technical Data

M.Wt:
223.27
Formula:
C12H17NO3
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage:
Store at -20°C
CAS No:
17397-89-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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