Home / Ubiquitin Ligase (E3) Inhibitors / CHIPOpt

CHIPOpt

Catalog #: 8044 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
8044/1
CHIPOpt
1 Image
Description: CHIP/STUB1 E3 ligase inhibitor

Purity: ≥95%

Product Details
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Biological Activity

CHIPOpt is a CHIP/STUB1 E3 ligase inhibitor. In vitro, CHIPOpt decreases phosphorylated tau ubiquitination, with little effect on unmodified tau. In Thioflavin T assays, CHIPOpt inhibits the ability of CHIP to suppress phosphorylated tau aggregation. FITC-CHIPOpt (Cat. No. 8045), a fluorescent CHIPOpt, is also available.

Technical Data

M.Wt:
757.84
Formula:
C39H47N7O9
Sequence:
LWWPD

(Modification: Leu-1 = N-terminal Ac)

Solubility:
Soluble to 2 mg/ml in 0.01M PBS
Purity:
≥95%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

FAQs

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