Home / Caged Compounds / ci-IP3/PM

ci-IP3/PM

Catalog #: 6210
9 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6210/10U
ci-IP3/PM | CAS No. 1009832-82-9 | Caged Compounds
1 Image
Description: Caged inositol triphosphate

Chemical Name: 6-O-[(4,5-Dimethoxy-2-nitrophenyl)methyl]-2,3-O-(1-methylethylidene)-D-myo-Inositol 1,4,5-tris[bis[(1-oxopropoxy)methyl]phosphate]

Purity: ≥98%

Product Details
Citations (9)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

ci-IP3/PM is a caged inositol triphosphate. Cell permeable. UV photolysis (λ = 330 nm) in HeLa cells releases i-IP3, promoting Ca2+-release from internal stores.

F 127 (Cat. No. 6253) for the solubilization of ci-IP3/PM is also available.

Technical Data

M.Wt:
1171.87
Formula:
C42H64NO31P3
Solubility:
Soluble in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1009832-82-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

COA view current batch
Or select another batch:
View Batch
SDS
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for ci-IP3/PM

The citations listed below are publications that use Tocris products. Selected citations for ci-IP3/PM include:

9 Citations: Showing 1 - 9

  1. Pharmacological potentiators of the calcium signaling cascade identified by high-throughput screening.
    Authors: Tiziano Et al.
    PNAS Nexus  2023;2:pgac288
  2. Disruption of Mitochondrial-associated ER membranes by HIV-1 tat protein contributes to premature brain aging.
    Authors: Jonathan Et al.
    CNS Neurosci Ther  2023;29:365-377
  3. Segregated cation flux by TPC2 biases Ca2+ signaling through lysosomes.
    Authors: Yu Et al.
    Nat Commun  2022;13:4481
  4. Functional determination of calcium-binding sites required for the activation of inositol 1,4,5-trisphosphate receptors.
    Authors: Sundeep Et al.
    Proc Natl Acad Sci U S A  2022;119:e2209267119
  5. Omnitemporal choreographies of all five STIM/Orai and IP3Rs underlie the complexity of mammalian Ca2+ signaling.
    Authors: David I Et al.
    Cell Rep  2021;34:108760
  6. A protocol for detecting elemental calcium signals (Ca2+ puffs) in mammalian cells using total internal reflection fluorescence microscopy.
    Authors: David I Et al.
    STAR Protoc  2021;2:100618
  7. The Mitochondrial Ca2+ uniporter is a central regulator of interorganellar Ca2+ transfer and NFAT activation.
    Authors: David I Et al.
    J Biol Chem  2021;297:101174
  8. CREB regulates the expression of type 1 inositol 1,4,5-trisphosphate receptors.
    Authors: Sundeep Et al.
    J Cell Sci  2021;134
  9. Fluoride exposure alters Ca2+ signaling and mitochondrial function in enamel cells.
    Authors: Vinu Et al.
    Sci Signal  2020;13

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for ci-IP3/PM

There are currently no reviews for this product. Be the first to review ci-IP3/PM and earn rewards!

Have you used ci-IP3/PM?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.