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CIA 1

Catalog #: 7494 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7494/10
7494/50
CIA 1 | CAS No. 1049691-47-5 | Additional Nuclear Receptor Compounds
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Description: COUP-TFII inhibitor

Chemical Name: N-[2-(3,4-Dimethoxyphenyl)ethyl]-6-methylthieno[2,3-d]pyrimidin-4-amine hydrochloride

Purity: ≥98%

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Biological Activity

CIA 1 is an inhibitor of the nuclear receptor COUP-TFII (IC50 ranged from 1.2 μM to 7.6 μM, in prostate cancer cell lines). In vitro, CIA 1 inhibits growth of multiple prostate cancer cell lines and suppresses COUP-TFII activity to regulate its target genes. In vivo, CIA 1 reduces tumor growth in prostate cancer xenograft mouse models.

Technical Data

M.Wt:
365.88
Formula:
C17H19N3O2S.HCl
Solubility:
Soluble to 20 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1049691-47-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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