Cilostazol
Chemical Name: 6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone
Purity: ≥99%
Biological Activity
Cilostazol is a potent phosphodiesterase III A (PDE3A) inhibitor (IC50 = 0.2 μM) and inhibitor of adenosine uptake. Has antimitogenic, antithrombotic, vasodilatory and cardiotonic properties in vivo. Also affects lipid levels in vivo.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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General pharmacological properties of cilostazol, a new antithrombotic drug. Part I: effects on the central nervous system.
Shintani et al.
Arzneimittelforschung, 1985;35:1157 -
General pharmacological properties of cilostazol, a new antithrombotic drug. Part II: effects on the peripheral organs.
Shintani et al.
Arzneimittelforschung, 1985;35:1163 -
The pharmacology of cilos.
Schror
Diabetes Obes.Metab., 2002;4:S14
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