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CIMBA hydrochloride

Catalog #: 7812 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7812/10
CIMBA hydrochloride | Estrogen and Related Receptor Antagonists
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Description: Potent and selective G protein-coupled estrogen receptor (GPER) antagonist

Chemical Name: N-[2-Cyclohexyl-4-(1-methylethyl)phenyl]-4-methoxybenzenemethanamine hydrochloride

Purity: ≥98%

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Biological Activity

CIMBA hydrochloride is a potent G protein-coupled estrogen receptor (GPER) antagonist (IC50 = 75 nM). In vivo, it prevents the formation of estrogen-induced cholesterol gallstones by inhibiting the GPER pathway in female ovariectomized mice.

Technical Data

M.Wt:
373.97
Formula:
C23H31NO.HCl
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under licence from Saint Louis University.

Product Datasheets

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