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CINPA 1

Catalog #: 5605
1 Citation Datasheet / COA / SDS

Discontinued Product

5605 has been discontinued.
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CINPA 1 | CAS No. 102636-74-8 | Constitutive Androstane Receptor Antagonists
1 Image
Description: Potent CAR antagonist

Chemical Name: Ethyl [5-[(diethylamino)acetyl]-10,11-dihydro-5H-dibenz[b,f]azepin-3-yl]carbamate

Purity: ≥98%

Product Details
Citations (1)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

CINPA 1 is a potent CAR antagonist (IC50 = 70 nM). Exhibits >90-fold selectivity for CAR over pregnane X receptor (PXR). Also selective over a panel of other nuclear receptors including FXR, LXR, PPARγ and RXR.

Technical Data

M.Wt:
395.49
Formula:
C23H29N3O3
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
102636-74-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citation for CINPA 1

The citations listed below are publications that use Tocris products. Selected citations for CINPA 1 include:

1 Citation: Showing 1 - 1

  1. Lack of CAR impacts neuronal function and cerebrovascular integrity in vivo.
    Authors: Boussadia Et al.
    Exp Neurol  2016;283:39

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