Home / VIP Receptor Antagonists / [D-p-Cl-Phe6,Leu17]-VIP

[D-p-Cl-Phe6,Leu17]-VIP

Catalog #: 3054
4 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3054/1
[D-p-Cl-Phe6,Leu17]-VIP
1 Image
Description: Selective VIP receptor antagonist

Purity: ≥95%

Product Details
Citations (4)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

[D-p-Cl-Phe6,Leu17]-VIP is a selective vasoactive intestinal peptide (VIP) receptor antagonist (IC50 = 125.8 nM). Displays no activity on glucagon, secretin or GRF receptors.

Technical Data

M.Wt:
3342.24
Formula:
C148H239ClN44O42
Sequence:
HSDAVFTDNYTRLRKQLAVKKYLNSILN

(Modifications: Phe-6 = p-Cl-D-Phe, Asn-34 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in water
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
102805-45-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for [D-p-Cl-Phe6,Leu17]-VIP

The citations listed below are publications that use Tocris products. Selected citations for [D-p-Cl-Phe6,Leu17]-VIP include:

4 Citations: Showing 1 - 4

  1. PACAP and VIP Inhibit the Invasiveness of Glioblastoma Cells Exposed to Hypoxia through the Regulation of HIFs and EGFR Expression.
    Authors: Maugeri Et al.
    Sci Rep  2016;7:139
  2. Manipulating circadian clock neuron firing rate resets molecular circadian rhythms and behavior.
    Authors: Jones Et al.
    Nat Neurosci  2015;18:373
  3. Parasympathetic innervation regulates tubulogenesis in the developing salivary gland.
    Authors: Nedvetsky Et al.
    Dev Cell  2014;30:449
  4. Dynamic interactions mediated by nonredundant signaling mechanisms couple circadian clock neurons.
    Authors: Evans Et al.
    Neuron  2013;80:973

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