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DPTN

Catalog #: 7628 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7628/50
7628/10
DPTN | CAS No. 325767-87-1 | Adenosine A3 R
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Description: Potent and selective A3 adenosine receptor antagonist

Chemical Name: N-[4-(3,5-Dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-3-pyridinecarboxamide dihydrochloride

Purity: ≥98%

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Biological Activity

DPTN is a potent and selective A3 adenosine receptor antagonist (Ki values are in the range 0.36 - 1.65 nM (hA3AR) and 1.6 - 8.53 nM (rA3AR)). Reduces intrapulmonary pressure when combined with Dexamethasone (Cat. No. 1126). Readily crosses the blood brain barrier in rats.

Technical Data

M.Wt:
459.39
Formula:
C22H18N4OS.2HCl
Solubility:
Soluble to 20 mM in DMSO with gentle warming
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
325767-87-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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