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Ellipticine

Catalog #: 3357
2 Citations Datasheet / COA / SDS

Discontinued Product

3357 has been discontinued.
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Ellipticine | CAS No. 519-23-3 | DNA Topoisomerase Inhibitors
1 Image
Description: Antitumor and intercalating agent; inhibits DNA topoisomerase II

Chemical Name: 5,11-Dimethyl-6H-pyrido[4,3-b]carbazole

Purity: ≥97%

Product Details
Citations (2)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Ellipticine is a naturally occurring plant alkaloid with antitumor activity. DNA intercalating agent; blocks DNA topoisomerase II activity. Prevents p53 phosphorylation in lung cancer cells.

Technical Data

M.Wt:
246.31
Formula:
C17H14N2
Solubility:
Soluble to 50 mM in DMSO
Purity:
≥97%
Storage:
Store at +4°C
CAS No:
519-23-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for Ellipticine

The citations listed below are publications that use Tocris products. Selected citations for Ellipticine include:

2 Citations: Showing 1 - 2

  1. IDA is a broad-spectrum enterovirus replication inhibitor that selectively targets the virus internal ribosomal entry site.
    Authors: Hou Et al.
    J Gen Virol  2016;97:1122
  2. Decreased miR122 in hepatocellular carcinoma leads to chemoresistance with increased arginine.
    Authors: Kishikawa Et al.
    Oncotarget  2015;6:8339

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