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Escitalopram oxalate

Catalog #: 4796
4 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4796/10
4796/50
Escitalopram oxalate | CAS No. 219861-08-2 | 5-HT Transporter Inhibitors
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Description: Selective serotonin reuptake inhibitor (SSRI)

Chemical Name: (+)-(S)-1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile oxalate

Purity: ≥98%

Product Details
Citations (4)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Escitalopram oxalate is a selective 5-HT reuptake inhibitor (Ki values are 0.89, 8150, and 10500 nM for serotonin, noradrenalin, and dopamine transporters respectively). Escitalopram oxalate is an S-enantiomer and eutomer of citalopram (Cat. No. 1427).

Technical Data

M.Wt:
414.43
Formula:
C20H21FN2O.C2H2O4
Solubility:
Soluble to 50 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
219861-08-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for Escitalopram oxalate

The citations listed below are publications that use Tocris products. Selected citations for Escitalopram oxalate include:

4 Citations: Showing 1 - 4

  1. Psychedelic-inspired drug discovery using an engineered biosensor.
    Authors: William C Et al.
    Cell  2021;184:2779-2792.e18
  2. Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning.
    Authors: Henry A Et al.
    Cell  2020;183:1986-2002.e26
  3. Escitalopram, a selective serotonin reuptake inhibitor, inhibits voltage-dependent K+ channels in coronary arterial smooth muscle cells.
    Authors: Il-Whan Et al.
    Korean J Physiol Pharmacol  2017;21:415-421
  4. Generation of serotonin neurons from human pluripotent stem cells.
    Authors: Lu Et al.
    J Exp Med  2016;34:89

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