Exendin-3 (9-39) amide

Catalog # Availability Size / Price Qty
2081/1
Exendin-3 (9-39) amide
1 Image
Description: Potent GLP-1 receptor antagonist

Purity: ≥95%

Product Details
Citations (5)
Supplemental Products
Reviews

Biological Activity

Exendin-3 (9-39) amide is a potent and selective GLP-1 receptor antagonist (Kd = 1.7 nM at cloned human GLP-1 receptors). Inhibits cAMP production and insulin release induced by GLP-1 (7-36), exendin-3 (IC50 = 20 nM) and exendin-4. Blocks the inhibitory effect of GLP-1 on food intake in rats.

Technical Data

M.Wt:
3369.79
Formula:
C149H234N40O47S
Sequence:
DLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS

(Modifications: Ser-31 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in water
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
133514-43-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for Exendin-3 (9-39) amide

The citations listed below are publications that use Tocris products. Selected citations for Exendin-3 (9-39) amide include:

5 Citations: Showing 1 - 5

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