FFN 206 dihydrochloride
Chemical Name: 4-(2-Aminoethyl)-7-(methylamino)-2H-1-benzopyran-2-one dihydrochloride
Purity: ≥99%
Biological Activity
FFN 206 dihydrochloride is a fluorescent VMAT2 substrate (IC50 app = 1.15 μM). Allows detection of VMAT2 subcellular locations in cell culture. Exhibits no detectable inhibition of DAT. Excitation maximum = 369 nm; emission maximum = 464 nm.Optical Data for FFN 206 dihydrochloride
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The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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New fluorescent substrate enables quantitative and high-throughput examination of vesicular monoamine transporter 2 (VMAT2).
Hu et al.
ACS Chem.Biol., 2013;8:1947
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Citations for FFN 206 dihydrochloride
The citations listed below are publications that use Tocris products. Selected citations for FFN 206 dihydrochloride include:
2 Citations: Showing 1 - 2
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Drosophila Ptp4E regulates vesicular packaging for monoamine-neuropeptide co-transmission.
Authors: Simon C Et al.
J Cell Sci 2019;132
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Merkel cells activate sensory neural pathways through adrenergic synapses.
Authors: Hoffman Et al.
Neuron 2018;100:1401
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