FFN 511
Chemical Name: 9-(2-Aminoethyl)-2,3,6,7-tetrahydro-1H,5H,11H-[1]-benzopyrano[6,7,8-ij]quinolizin-11-one
Purity: ≥99%
Biological Activity
FFN 511 is a fluorescent false neurotransmitter (FFN). Targets neuronal vesicular monoamine transporter (VMAT) 2; inhibits serotonin binding to VMAT2 (IC50 = 1 μM). Excitation and emission maxima are 406 and 501 nm in pH 7 buffer, respectively.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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Fluorescent false neurotransmitters visualize DA release from individual presynaptic terminals.
Gubernator et al.
Science, 2009;324:1441 -
DA release at individual presynaptic terminals visualized with FFNs.
Zhang et al.
J.Vis.Exp., 2009;30
Product Datasheets
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