Home / Cyclooxygenase Inhibitors / FK 3311

FK 3311

Catalog #: 2776 Datasheet / COA / SDS

Discontinued Product

2776 has been discontinued.
View all Cyclooxygenase Inhibitors products.
FK 3311 | CAS No. 116686-15-8 | Cyclooxygenase Inhibitors
1 Image
Description: Cyclooxygenase-2 (COX-2) inhibitor

Chemical Name: N-[4-Acetyl-2-(2,4-difluorophenoxy)phenyl]methanesulfonamide

Purity: ≥98%

Product Details
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

FK 3311 is a cyclooxygenase-2 (COX-2) inhibitor. Inhibits zymosan-induced prostaglandin E2 production by rat peritoneal neutrophils in vitro and adjuvant-induced arthritis in vivo. Anti-inflammatory.

Technical Data

M.Wt:
341.33
Formula:
C15H13F2NO4S
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥98%
Storage:
Store at RT
CAS No:
116686-15-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Studies on antiinflammatory agents. I. Synthesis and pharmacological properties of 2'-phenoxy-methanesulfonanilide derivatives.
    Tsuji et al.
    Chem.Pharm.Bull., 1992;40:2399
  2. Effects of the COX-2 inhibitor FK3311 on ischemia-reperfusion injury in the rat lung.
    Otani et al.
    J.Invest.Surg., 2007;20:175
  3. Studies on antiinflammatory agents. III. Synthesis and pharmacological properties of metabolites of 4'-acetyl-2'-(2,4-difluorophenoxy)methanesulfonanilide (FK3311).
    Nakamura et al.
    Chem.Pharm.Bull., 1993;41

Product Datasheets

Reconstitution Calculator
Molarity Calculator

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for FK 3311

There are currently no reviews for this product. Be the first to review FK 3311 and earn rewards!

Have you used FK 3311?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.