Foxy 5
Purity: ≥95%
Biological Activity
Foxy 5 is a Wnt5a peptide mimetic. Impairs migration and invasion of 4T1 breast cancer cells in vitro. Also inhibits metastasis of inoculated 4T1 cells in mice.Technical Data
(Modifications: Met-1 = N-Formyl)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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The Wnt-5a-derived hexapeptide Foxy-5 inhibits breast cancer metastasis in vivo by targeting cell motility.
Säfholm et al.
Clin.Cancer Res., 2008;14:6556 -
A formylated hexapeptide ligand mimics the ability of Wnt-5a to impair migration of human breast epithelial cells.
Säfholm et al.
J.Biol.Chem., 2006;281:2740
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Citation for Foxy 5
The citations listed below are publications that use Tocris products. Selected citations for Foxy 5 include:
1 Citation: Showing 1 - 1
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Commitment and oncogene-induced plasticity of human stem cell-derived pancreatic acinar and ductal organoids.
Authors: Ling Et al.
Cell Stem Cell 2021;28:1090-1104.e6
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