G418 disulfate salt
Biological Activity
G418 disulfate salt is an aminoglycosidic antibiotic. Inhibits protein synthesis in both prokaryotic and eukaryotic cells. Used for selection of eukaryotic cells transfected with the neo gene.This product has been cell culture tested.
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
- This product has been cell culture tested
Background References
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Antibiotic G-418, a new Micromonospora-produced aminoglycoside with activity against protozoa and helminths: fermentation, isolation and preliminary characterization.
Wagman et al.
Antimicrob.Agents Chemother., 1974;6:144 -
G-418, an elongation inhibitor of 80 S ribosomes.
Bar-Nun et al.
Biochim.Biophys.Acta., 1983;741:123 -
Suppression of a nonsense mutation in mammalian cells in vivo by the aminoglycoside antibiotics G-418 and paromo.
Burke and Mogg
Nucleic Acids Res., 1985;13:6265
Product Datasheets
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Citation for G418 disulfate salt
The citations listed below are publications that use Tocris products. Selected citations for G418 disulfate salt include:
1 Citation: Showing 1 - 1
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Curcumin-induced antitumor effects on triple-negative breast cancer patient-derived xenograft tumor mice through inhibiting salt-induced kinase-3 protein.
Authors: Yuan-Soon Et al.
J Food Drug Anal 2021;29:622-637
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