γDGG
Chemical Name: γ-D-Glutamylglycine
Purity: ≥99%
Biological Activity
γDGG is a broad spectrum glutamate receptor antagonist.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Glutamate neurotransmission in the cerebellar interposed nuclei: involvement in classical conditioned eyeblinks and neuronal activity.
Aksenov et al.
J.Neurophysiol., 2005;93:44 -
Structure-activity relations of dipeptide antagonists of excitatory amino acids.
Jones et al.
Neuroscience, 1984;13:573
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Citations for γDGG
The citations listed below are publications that use Tocris products. Selected citations for γDGG include:
3 Citations: Showing 1 - 3
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The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse.
Authors: Chen Et al.
J Neurosci 2013;33:8336
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Synaptotagmin has an essential function in synaptic vesicle positioning for synchronous release in addition to its role as a calcium sensor.
Authors: Young and Neher
Neuron 2009;63:482
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In vivo metabotropic glutamate receptor 5 (mGluR5) antagonism prevents cocaine-induced disruption of postsynaptically maintained mGluR5-dependent long-term depression.
Authors: Grueter Et al.
J Neurosci 2008;28:9261
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