GoSlo SR 5-69
Chemical Name: Sodium 1-Amino-9,10-dioxo-4-((5,6,7,8-tetrahydronaphthalen-2-yl)amino)-9,10-dihydroanthracene-2-sulfonate
Purity: ≥98%
Biological Activity
GoSlo SR 5-69 is a BK channel activator (EC50 = 251 nM). Shifts the voltage required for half maximal negatively (DV1/2 = -104 mV).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels.
Schewe et al.
Science, 2019;363:875 -
Development of GoSlo-SR-5-69, a potent activator of large conductance Ca2+-activated K+ (BK) channels.
Roy et al.
Eur.J.Med.Chem., 2014;75:426
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