GW 542573X

Catalog # Availability Size / Price Qty
4311/10
4311/50
GW 542573X | CAS No. 660846-41-3 | Ca2+-Activated Potassium Channel Activators
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Description: Selective KCa2.1 (SK) channel activator

Chemical Name: 4-[[[[(2-Methoxyphenyl)amino]carbonyl]oxy]methyl]-piperidinecarboxylic acid-1,1-dimethylethyl ester

Purity: ≥99%

Product Details
Reviews (1)

Biological Activity

GW 542573X is an activator of small-conductance Ca2+-activated K+ channels (KCa2); selective for KCa2.1 (EC50 = 8.2 μM in HEK293 cells expressing hKCa2.1) with the profile hKCa2.1 > hKCa2.2 = hKCa2.3 > hKCa3.1 (IK).

Technical Data

M.Wt:
364.44
Formula:
C19H28N2O5
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
660846-41-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Systemic administration of GW in mice
By Anonymous on 05/30/2018

Our lab has used GW in several behavior studies over the last few years. Our results have always been reliable and reproducible using systemic administrations of GW. We will surely continue using this product.


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