Human ABCA13 Antibody

Catalog # Availability Size / Price Qty
MAB11195-100
MAB11195-SP
ABCA13 in Human Hippocampus.
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Human ABCA13 Antibody Summary

Species Reactivity
Human
Specificity
Detects Human ABCA13 peptide in direct Elisas.
Source
Monoclonal Rabbit IgG Clone # 2379B
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Synthetic peptide within aminoacids 4700-4750 of the Human ABCA13 protein

Accession # Q86UQ4
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Immunohistochemistry
3-25 µg/mL
Immersion fixed paraffin-embedded sections of human brain hippocampus

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Immunohistochemistry View Larger

ABCA13 in Human Hippocampus. ABCA13 was detected in immersion fixed paraffin-embedded sections of human brain hippocampus using Rabbit Anti-Human ABCA13 Monoclonal Antibody (Catalog # MAB11195) at 3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Rabbit IgG VisUCyte™ HRP Polymer Antibody (VC003). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (CTS013). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to lymphocytes in germinal centers. Staining was performed using our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
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Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: ABCA13

ATP-binding cassette sub-family A member 13, also known as ABCA13, is a protein that belongs to the ATP-binding cassette family of transporter proteins, a large family with at least 48 members and 7 gene subfamilies. Human ABCA13 is one of the largest known ABC transportes with 12 or more transmembrane alpha-helix domains that likely arrange to form a single central chamber with multiple substrate binding sites. Human ABCA13 has been shown to be associated with psychiatric disorders like schizophrenia and bipolar disorder.

Long Name
ATP Binding Cassette Subfamily A Member 13
Entrez Gene IDs
154664 (Human)
Alternate Names
ABCA13; ATP binding cassette transporter A13; ATP-binding cassette sub-family A member 13; ATP-binding cassette, sub-family A (ABC1), member 13; DKFZp313D2411; EC 2.7.11.25; EC 3.6.3; FLJ16398; FLJ33876; FLJ33951

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