Human Aminopeptidase N/CD13 (NP_001141) VersaClone cDNA

Human Aminopeptidase N/CD13 (NP_001141) VersaClone cDNA Summary

Specifications

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Background: Aminopeptidase N/CD13

The ANPEP gene encodes Aminopeptidase N (APN), also known as CD13 or Alanyl Aminopeptidase. The deduced amino acid sequence of APN consists of a short cytoplasmic tail, a transmembrane region, a Ser/Thr rich region, and a zinc metalloproteinase domain. Widely expressed in many cells, tissues, and species, APN cleaves the N-terminal amino acids from bioactive peptides, leading to their inactivation or degradation. It has putative involvement in several biological processes including antigen processing and presentation, cell adhesion, tumor invasion and metastasis, neurotransmitter degradation, and it also serves as a receptor for certain coronaviruses.

Related Research Areas

• Acute Lymphoblastic Leukemia
• Acute Myeloid Leukemia
• Adipose-derived Stem Cell Markers
• Cancer Stem Cell Markers
• Epithelial Cell Markers and Intracellular Molecules
• Granulocyte Markers
• Infectious Diseases
• Mesenchymal Stem Cell Markers
• Metalloproteases and Regulators
• Monocyte Markers
• Myeloid Lineage Markers
• Renin-Angiotensin System
• Search Bioprocessing Enzymes
• Surface Ectodermal Cells
• Vasoactive Peptide Hormones and Regulators