Human Aminopeptidase P1/XPNPEP1 MAb (Clone 409124)
Human Aminopeptidase P1/XPNPEP1 MAb (Clone 409124) Summary
Met1-Gln622
Accession # Q9NQW7
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Aminopeptidase P1/XPNPEP1 in Human Bladder Cancer Tissue. Aminopeptidase P1/XPNPEP1 was detected in immersion fixed paraffin-embedded sections of human bladder cancer tissue using Mouse Anti-Human Aminopeptidase P1/XPNPEP1 Monoclonal Antibody (Catalog # MAB29701) at 25 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counterstained with hematoxylin (blue). Specific labeling was localized to the cytoplasm and plasma membrane of smooth muscle cells. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Aminopeptidase P1/XPNPEP1
The human XPNPEP1 gene encodes aminopeptidase P1 (APP1), which is also known as X-prolyl aminopeptidase. Aminopeptidase P1 is a member of the M24 family of metalloproteases, which also contains methionine aminopeptidases, X-Pro dipeptidase, aminopeptidase P2, aminopeptidase P homolog, proliferation-associated protein 1, and suppressor of Ty homolog or chromatin-specific transcription elongation factor large subunit. It is a soluble enzyme, in contrast to the GPI-anchored Aminopeptidase P2 encoded by XPNPEP2. Human Aminopeptidase P1 is widely expressed. The amino acid sequence of human Aminopeptidase P1 is 99%, 97%, 95%, 74% and 73% identical to that of canine, bovine, mouse/rat, Xenopus and zebrafish, respectively.
Product Datasheets
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